HUMANIZATION AND FRAMEWORK GRAFTING

Antibody Synthesis Services

Antibody humanization

from $2,000 per gene, 3-5 weeks, request a quote

Client provides sequence information and desirable antibody format.

We will analyze the sequences, identify the best matching human frameworks, design human equivalents, assemble them using our block-based gene assembling technology and clone into our bicistronic mammalian expression vector.

We deliver ~10μg of spin-column purified plasmid DNA and detailed project report containing the plasmid map, sequence trace files and annotated sequences of the expression cassettes.

We recommend using this in combination with our affinity maturation service.

Framework grafting

from $2,000 per gene, 3-5 weeks, request a quote

Client provides sequence information and desirable antibody format.

We will analyze the sequences, identify the best matching frameworks from the available frameworks of the species specified by the Client, design synthetic equivalents, assemble them using our block-based gene assembling technology and clone into our bicistronic mammalian expression vector.

We deliver ~10μg of spin-column purified plasmid DNA and detailed project report containing the plasmid map, sequence trace files and annotated sequences of the expression cassettes.

We recommend using this in combination with our affinity maturation service.

Custom gene design and de novo synthesis

Please inquire

Genes will be assembled using our block-based gene assembling technology and clone into a vector of your choice.

We deliver ~10μg of spin-column purified plasmid DNA and detailed project report containing the plasmid map, sequence trace files and annotated sequences of the expression cassettes.